Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

BACKGROUND AND OBJECTIVES: Chronic widespread pain (CWP) is a common disorder affecting ∼10% of the general population and has an estimated heritability of 48–52%. In the first large-scale genome-wide association study (GWAS) meta-analysis, we aimed to identify common genetic variants associated wit...

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Detalles Bibliográficos
Autores principales: Peters, Marjolein J, Broer, Linda, Willemen, Hanneke L D M, Eiriksdottir, Gudny, Hocking, Lynne J, Holliday, Kate L, Horan, Michael A, Meulenbelt, Ingrid, Neogi, Tuhina, Popham, Maria, Schmidt, Carsten O, Soni, Anushka, Valdes, Ana M, Amin, Najaf, Dennison, Elaine M, Eijkelkamp, Niels, Harris, Tamara B, Hart, Deborah J, Hofman, Albert, Huygen, Frank J P M, Jameson, Karen A, Jones, Gareth T, Launer, Lenore J, Kerkhof, Hanneke J M, de Kruijf, Marjolein, McBeth, John, Kloppenburg, Margreet, Ollier, William E, Oostra, Ben, Payton, Antony, Rivadeneira, Fernando, Smith, Blair H, Smith, Albert V, Stolk, Lisette, Teumer, Alexander, Thomson, Wendy, Uitterlinden, André G, Wang, Ke, van Wingerden, Sophie H, Arden, Nigel K, Cooper, Cyrus, Felson, David, Gudnason, Vilmundur, Macfarlane, Gary J, Pendleton, Neil, Slagboom, P Eline, Spector, Tim D, Völzke, Henry, Kavelaars, Annemieke, van Duijn, Cornelia M, Williams, Frances M K, van Meurs, Joyce B J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691951/
https://www.ncbi.nlm.nih.gov/pubmed/22956598
http://dx.doi.org/10.1136/annrheumdis-2012-201742

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