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Unusual Orange-Colored Choroidal Metastases

PURPOSE: To report the clinical and paraclinical features of two patients with orange- colored choroidal metastases in whom the primary cancers have not previously been associated with such lesions. CASE REPORT: Orange-colored choroidal lesions were detected on the fundus examination of one patient...

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Autores principales: Krema, Hatem, McGowan, Hugh, Tanzer, Herbert, Simpson, Rand, Laperriere, Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ophthalmic Research Center 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691979/
https://www.ncbi.nlm.nih.gov/pubmed/23825713
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author Krema, Hatem
McGowan, Hugh
Tanzer, Herbert
Simpson, Rand
Laperriere, Normand
author_facet Krema, Hatem
McGowan, Hugh
Tanzer, Herbert
Simpson, Rand
Laperriere, Normand
author_sort Krema, Hatem
collection PubMed
description PURPOSE: To report the clinical and paraclinical features of two patients with orange- colored choroidal metastases in whom the primary cancers have not previously been associated with such lesions. CASE REPORT: Orange-colored choroidal lesions were detected on the fundus examination of one patient with metastatic small cell neuroendocrine tumor of the larynx and oropharynx, and in another subject with metastatic alveolar soft part sarcoma of the leg. Although ultrasonographic characteristics of the choroidal masses were comparable to those of choroidal hemangiomas, fluorescein angiography revealed delayed initial fluorescence along with minimal fluorescence in subsequent phases of the angiogram which were in clear distinction from the earlier appearing and progressively intense fluorescence observed with circumscribed choroidal hemangiomas. CONCLUSION: Small cell neuroendocrine tumors and alveolar soft part sarcomas should be considered among the differential diagnoses for orange-colored choroidal metastases. Identifying these choroidal lesions could facilitate localizing the occult primary tumor. Fluorescein angiography may differentiate a unifocal orange choroidal metastasis from a circumscribed choroidal hemangioma.
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spelling pubmed-36919792013-07-02 Unusual Orange-Colored Choroidal Metastases Krema, Hatem McGowan, Hugh Tanzer, Herbert Simpson, Rand Laperriere, Normand J Ophthalmic Vis Res Case Report PURPOSE: To report the clinical and paraclinical features of two patients with orange- colored choroidal metastases in whom the primary cancers have not previously been associated with such lesions. CASE REPORT: Orange-colored choroidal lesions were detected on the fundus examination of one patient with metastatic small cell neuroendocrine tumor of the larynx and oropharynx, and in another subject with metastatic alveolar soft part sarcoma of the leg. Although ultrasonographic characteristics of the choroidal masses were comparable to those of choroidal hemangiomas, fluorescein angiography revealed delayed initial fluorescence along with minimal fluorescence in subsequent phases of the angiogram which were in clear distinction from the earlier appearing and progressively intense fluorescence observed with circumscribed choroidal hemangiomas. CONCLUSION: Small cell neuroendocrine tumors and alveolar soft part sarcomas should be considered among the differential diagnoses for orange-colored choroidal metastases. Identifying these choroidal lesions could facilitate localizing the occult primary tumor. Fluorescein angiography may differentiate a unifocal orange choroidal metastasis from a circumscribed choroidal hemangioma. Ophthalmic Research Center 2013-01 /pmc/articles/PMC3691979/ /pubmed/23825713 Text en © 2013 Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Case Report
Krema, Hatem
McGowan, Hugh
Tanzer, Herbert
Simpson, Rand
Laperriere, Normand
Unusual Orange-Colored Choroidal Metastases
title Unusual Orange-Colored Choroidal Metastases
title_full Unusual Orange-Colored Choroidal Metastases
title_fullStr Unusual Orange-Colored Choroidal Metastases
title_full_unstemmed Unusual Orange-Colored Choroidal Metastases
title_short Unusual Orange-Colored Choroidal Metastases
title_sort unusual orange-colored choroidal metastases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691979/
https://www.ncbi.nlm.nih.gov/pubmed/23825713
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