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DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept u...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692126/ https://www.ncbi.nlm.nih.gov/pubmed/23620293 http://dx.doi.org/10.1093/nar/gkt283 |
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author | Al Ait, Layal Yamak, Zaher Morgenstern, Burkhard |
author_facet | Al Ait, Layal Yamak, Zaher Morgenstern, Burkhard |
author_sort | Al Ait, Layal |
collection | PubMed |
description | DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept user-specified external information. In this article, we review some versions of the program that are available through ‘Göttingen Bioinformatics Compute Server’. In addition to previously described implementations, we present a new release of DIALIGN called ‘DIALIGN-PFAM’, which uses hits to the PFAM database for improved protein alignment. Our software is available through http://dialign.gobics.de/. |
format | Online Article Text |
id | pubmed-3692126 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-36921262013-06-25 DIALIGN at GOBICS—multiple sequence alignment using various sources of external information Al Ait, Layal Yamak, Zaher Morgenstern, Burkhard Nucleic Acids Res Articles DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept user-specified external information. In this article, we review some versions of the program that are available through ‘Göttingen Bioinformatics Compute Server’. In addition to previously described implementations, we present a new release of DIALIGN called ‘DIALIGN-PFAM’, which uses hits to the PFAM database for improved protein alignment. Our software is available through http://dialign.gobics.de/. Oxford University Press 2013-07 2013-04-24 /pmc/articles/PMC3692126/ /pubmed/23620293 http://dx.doi.org/10.1093/nar/gkt283 Text en © The Author(s) 2013. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Articles Al Ait, Layal Yamak, Zaher Morgenstern, Burkhard DIALIGN at GOBICS—multiple sequence alignment using various sources of external information |
title | DIALIGN at GOBICS—multiple sequence alignment using various sources of external information |
title_full | DIALIGN at GOBICS—multiple sequence alignment using various sources of external information |
title_fullStr | DIALIGN at GOBICS—multiple sequence alignment using various sources of external information |
title_full_unstemmed | DIALIGN at GOBICS—multiple sequence alignment using various sources of external information |
title_short | DIALIGN at GOBICS—multiple sequence alignment using various sources of external information |
title_sort | dialign at gobics—multiple sequence alignment using various sources of external information |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692126/ https://www.ncbi.nlm.nih.gov/pubmed/23620293 http://dx.doi.org/10.1093/nar/gkt283 |
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