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DIALIGN at GOBICS—multiple sequence alignment using various sources of external information

DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept u...

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Detalles Bibliográficos
Autores principales: Al Ait, Layal, Yamak, Zaher, Morgenstern, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692126/
https://www.ncbi.nlm.nih.gov/pubmed/23620293
http://dx.doi.org/10.1093/nar/gkt283
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author Al Ait, Layal
Yamak, Zaher
Morgenstern, Burkhard
author_facet Al Ait, Layal
Yamak, Zaher
Morgenstern, Burkhard
author_sort Al Ait, Layal
collection PubMed
description DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept user-specified external information. In this article, we review some versions of the program that are available through ‘Göttingen Bioinformatics Compute Server’. In addition to previously described implementations, we present a new release of DIALIGN called ‘DIALIGN-PFAM’, which uses hits to the PFAM database for improved protein alignment. Our software is available through http://dialign.gobics.de/.
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spelling pubmed-36921262013-06-25 DIALIGN at GOBICS—multiple sequence alignment using various sources of external information Al Ait, Layal Yamak, Zaher Morgenstern, Burkhard Nucleic Acids Res Articles DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept user-specified external information. In this article, we review some versions of the program that are available through ‘Göttingen Bioinformatics Compute Server’. In addition to previously described implementations, we present a new release of DIALIGN called ‘DIALIGN-PFAM’, which uses hits to the PFAM database for improved protein alignment. Our software is available through http://dialign.gobics.de/. Oxford University Press 2013-07 2013-04-24 /pmc/articles/PMC3692126/ /pubmed/23620293 http://dx.doi.org/10.1093/nar/gkt283 Text en © The Author(s) 2013. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Articles
Al Ait, Layal
Yamak, Zaher
Morgenstern, Burkhard
DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
title DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
title_full DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
title_fullStr DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
title_full_unstemmed DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
title_short DIALIGN at GOBICS—multiple sequence alignment using various sources of external information
title_sort dialign at gobics—multiple sequence alignment using various sources of external information
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692126/
https://www.ncbi.nlm.nih.gov/pubmed/23620293
http://dx.doi.org/10.1093/nar/gkt283
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