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D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation

We report a 71-year-old female who presented with rheumatoid arthritis complicated by proteinuria. She had been receiving D-penicillamine (D-Pc) for two years prior to presentation. A urinalysis showed proteinuria and hematuria which disappeared within 3 months after D-Pc was stopped. The renal hist...

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Detalles Bibliográficos
Autores principales: Mokuda, S., Onishi, M., Takasugi, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692153/
https://www.ncbi.nlm.nih.gov/pubmed/23814426
http://dx.doi.org/10.4103/0971-4065.111862
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author Mokuda, S.
Onishi, M.
Takasugi, K.
author_facet Mokuda, S.
Onishi, M.
Takasugi, K.
author_sort Mokuda, S.
collection PubMed
description We report a 71-year-old female who presented with rheumatoid arthritis complicated by proteinuria. She had been receiving D-penicillamine (D-Pc) for two years prior to presentation. A urinalysis showed proteinuria and hematuria which disappeared within 3 months after D-Pc was stopped. The renal histological findings showed focal proliferative glomerulonephritis with crescent formation. A total of 10 cases of D-Pc-induced glomerulonephritis with crescent formation without alveolar hemorrhage have previously been reported in the literature. To the best of our knowledge, this is the first case report in which the patient did not require any treatment.
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spelling pubmed-36921532013-06-28 D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation Mokuda, S. Onishi, M. Takasugi, K. Indian J Nephrol Case Report We report a 71-year-old female who presented with rheumatoid arthritis complicated by proteinuria. She had been receiving D-penicillamine (D-Pc) for two years prior to presentation. A urinalysis showed proteinuria and hematuria which disappeared within 3 months after D-Pc was stopped. The renal histological findings showed focal proliferative glomerulonephritis with crescent formation. A total of 10 cases of D-Pc-induced glomerulonephritis with crescent formation without alveolar hemorrhage have previously been reported in the literature. To the best of our knowledge, this is the first case report in which the patient did not require any treatment. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3692153/ /pubmed/23814426 http://dx.doi.org/10.4103/0971-4065.111862 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mokuda, S.
Onishi, M.
Takasugi, K.
D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
title D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
title_full D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
title_fullStr D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
title_full_unstemmed D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
title_short D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
title_sort d-penicillamine-induced glomerulonephritis with crescent formation: remission following drug discontinuation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692153/
https://www.ncbi.nlm.nih.gov/pubmed/23814426
http://dx.doi.org/10.4103/0971-4065.111862
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