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Microflora and periodontal disease
BACKGROUND: Periodontitis is a disease that affects and destroys the tissues that support teeth. Tissue damage results from a prolonged inflammatory response to an ecological shift in the composition of subgingival biofilms. Three bacterial species that constitute the red complex group, Porphyromona...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692174/ https://www.ncbi.nlm.nih.gov/pubmed/23814584 http://dx.doi.org/10.4103/1735-3327.109755 |
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author | Scapoli, Luca Girardi, Ambra Palmieri, Annalisa Testori, Tiziano Zuffetti, Francesco Monguzzi, Riccardo Lauritano, Dorina Carinci, Francesco |
author_facet | Scapoli, Luca Girardi, Ambra Palmieri, Annalisa Testori, Tiziano Zuffetti, Francesco Monguzzi, Riccardo Lauritano, Dorina Carinci, Francesco |
author_sort | Scapoli, Luca |
collection | PubMed |
description | BACKGROUND: Periodontitis is a disease that affects and destroys the tissues that support teeth. Tissue damage results from a prolonged inflammatory response to an ecological shift in the composition of subgingival biofilms. Three bacterial species that constitute the red complex group, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, are considered the main pathogens involved in periodontitis. MATERIALS AND METHODS: In the present study, a real-time polymerase chain reaction bases assay was designed to detect and quantify red complex species, then used to investigate 307 periodontal pocket samples from 127 periodontitis patients and 180 controls. RESULTS: Significant higher prevalence of red complex species and increased amount of P. gingivalis and T. denticola were detected in periodontal pocket of periodontitis patients. CONCLUSIONS: Results demonstrated that the test is a valuable tool to improve diagnosis of periodontal disease. |
format | Online Article Text |
id | pubmed-3692174 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36921742013-06-28 Microflora and periodontal disease Scapoli, Luca Girardi, Ambra Palmieri, Annalisa Testori, Tiziano Zuffetti, Francesco Monguzzi, Riccardo Lauritano, Dorina Carinci, Francesco Dent Res J (Isfahan) Original Article BACKGROUND: Periodontitis is a disease that affects and destroys the tissues that support teeth. Tissue damage results from a prolonged inflammatory response to an ecological shift in the composition of subgingival biofilms. Three bacterial species that constitute the red complex group, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, are considered the main pathogens involved in periodontitis. MATERIALS AND METHODS: In the present study, a real-time polymerase chain reaction bases assay was designed to detect and quantify red complex species, then used to investigate 307 periodontal pocket samples from 127 periodontitis patients and 180 controls. RESULTS: Significant higher prevalence of red complex species and increased amount of P. gingivalis and T. denticola were detected in periodontal pocket of periodontitis patients. CONCLUSIONS: Results demonstrated that the test is a valuable tool to improve diagnosis of periodontal disease. Medknow Publications & Media Pvt Ltd 2012-12 /pmc/articles/PMC3692174/ /pubmed/23814584 http://dx.doi.org/10.4103/1735-3327.109755 Text en Copyright: © Dental Research Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Scapoli, Luca Girardi, Ambra Palmieri, Annalisa Testori, Tiziano Zuffetti, Francesco Monguzzi, Riccardo Lauritano, Dorina Carinci, Francesco Microflora and periodontal disease |
title | Microflora and periodontal disease |
title_full | Microflora and periodontal disease |
title_fullStr | Microflora and periodontal disease |
title_full_unstemmed | Microflora and periodontal disease |
title_short | Microflora and periodontal disease |
title_sort | microflora and periodontal disease |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692174/ https://www.ncbi.nlm.nih.gov/pubmed/23814584 http://dx.doi.org/10.4103/1735-3327.109755 |
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