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Metastatic anaplastic large cell lymphoma of the oral cavity
Lymphoma is a malignant neoplasm of lymphoid tissue which is divided into 2 groups: Hodgkin and non-Hodgkin. About 85% of non-Hodgkin lymphomas are B-cell lymphomas, and T-cell lymphomas are unusual. Anaplastic large cell lymphoma (ALCL) is a kind of non-Hodgkin lymphoma with T or NK cell origin tha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692192/ https://www.ncbi.nlm.nih.gov/pubmed/23814554 |
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author | Deyhimi, Parviz Keshani, Forouz Azmoudeh, Faezeh Hashemzadeh, Zahra |
author_facet | Deyhimi, Parviz Keshani, Forouz Azmoudeh, Faezeh Hashemzadeh, Zahra |
author_sort | Deyhimi, Parviz |
collection | PubMed |
description | Lymphoma is a malignant neoplasm of lymphoid tissue which is divided into 2 groups: Hodgkin and non-Hodgkin. About 85% of non-Hodgkin lymphomas are B-cell lymphomas, and T-cell lymphomas are unusual. Anaplastic large cell lymphoma (ALCL) is a kind of non-Hodgkin lymphoma with T or NK cell origin that is rarely seen in the oral cavity and only 10 cases have been reported up to now. Here we present a case of ALCL metastasized to the oral cavity in a 32- year- old man with pervious history of ALCL which caused an ulceration in the posterior area of the hard palate. Radiography showed irregular resorption of alveolar bone. Histopathologic examination of the incisional biopsy revealed neoplastic proliferation of large and bizarre cells with hyperchromatic nuclei and numerous giant cells and atypical mitoses. Immunohistochemistry markers (CK, LCA, CD3, CD30, CD20) confirmed the diagnosis of ALCL. |
format | Online Article Text |
id | pubmed-3692192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36921922013-06-28 Metastatic anaplastic large cell lymphoma of the oral cavity Deyhimi, Parviz Keshani, Forouz Azmoudeh, Faezeh Hashemzadeh, Zahra Dent Res J (Isfahan) Case Report Lymphoma is a malignant neoplasm of lymphoid tissue which is divided into 2 groups: Hodgkin and non-Hodgkin. About 85% of non-Hodgkin lymphomas are B-cell lymphomas, and T-cell lymphomas are unusual. Anaplastic large cell lymphoma (ALCL) is a kind of non-Hodgkin lymphoma with T or NK cell origin that is rarely seen in the oral cavity and only 10 cases have been reported up to now. Here we present a case of ALCL metastasized to the oral cavity in a 32- year- old man with pervious history of ALCL which caused an ulceration in the posterior area of the hard palate. Radiography showed irregular resorption of alveolar bone. Histopathologic examination of the incisional biopsy revealed neoplastic proliferation of large and bizarre cells with hyperchromatic nuclei and numerous giant cells and atypical mitoses. Immunohistochemistry markers (CK, LCA, CD3, CD30, CD20) confirmed the diagnosis of ALCL. Medknow Publications & Media Pvt Ltd 2012-12 /pmc/articles/PMC3692192/ /pubmed/23814554 Text en Copyright: © Dental Research Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Deyhimi, Parviz Keshani, Forouz Azmoudeh, Faezeh Hashemzadeh, Zahra Metastatic anaplastic large cell lymphoma of the oral cavity |
title | Metastatic anaplastic large cell lymphoma of the oral cavity |
title_full | Metastatic anaplastic large cell lymphoma of the oral cavity |
title_fullStr | Metastatic anaplastic large cell lymphoma of the oral cavity |
title_full_unstemmed | Metastatic anaplastic large cell lymphoma of the oral cavity |
title_short | Metastatic anaplastic large cell lymphoma of the oral cavity |
title_sort | metastatic anaplastic large cell lymphoma of the oral cavity |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692192/ https://www.ncbi.nlm.nih.gov/pubmed/23814554 |
work_keys_str_mv | AT deyhimiparviz metastaticanaplasticlargecelllymphomaoftheoralcavity AT keshaniforouz metastaticanaplasticlargecelllymphomaoftheoralcavity AT azmoudehfaezeh metastaticanaplasticlargecelllymphomaoftheoralcavity AT hashemzadehzahra metastaticanaplasticlargecelllymphomaoftheoralcavity |