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Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration

BACKGROUND: Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and surfactants are potentially good colloidal drug carriers. Thymoquinone is the main bioactive compound of Nigella sativa. In this study, the preparation, gastroprotective effects, and pharmacokinetic (PK) prope...

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Detalles Bibliográficos
Autores principales: Abdelwahab, Siddig Ibrahim, Sheikh, Bassem Yousef, Taha, Manal Mohamed Elhassan, How, Chee Wun, Abdullah, Rasedee, Yagoub, Umar, El-Sunousi, Rashad, Eid, Eltayeb EM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692342/
https://www.ncbi.nlm.nih.gov/pubmed/23818776
http://dx.doi.org/10.2147/IJN.S44108