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Transgenic Increase in N-3/N-6 Fatty Acid Ratio Reduces Maternal Obesity-Associated Inflammation and Limits Adverse Developmental Programming in Mice

Maternal and pediatric obesity has risen dramatically over recent years, and is a known predictor of adverse long-term metabolic outcomes in offspring. However, which particular aspects of obese pregnancy promote such outcomes is less clear. While maternal obesity increases both maternal and placent...

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Detalles Bibliográficos
Autores principales: Heerwagen, Margaret J. R., Stewart, Michael S., de la Houssaye, Becky A., Janssen, Rachel C., Friedman, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692451/
https://www.ncbi.nlm.nih.gov/pubmed/23825686
http://dx.doi.org/10.1371/journal.pone.0067791