Activation of Sterol Regulatory Element Binding Protein and NLRP3 Inflammasome in Atherosclerotic Lesion Development in Diabetic Pigs

BACKGROUND: Aberrantly elevated sterol regulatory element binding protein (SREBP), the lipogenic transcription factor, contributes to the development of fatty liver and insulin resistance in animals. Our recent studies have discovered that AMP-activated protein kinase (AMPK) phosphorylates SREBP at...

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Detalles Bibliográficos
Autores principales: Li, Yu, Xu, Shanqin, Jiang, Bingbing, Cohen, Richard A., Zang, Mengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692453/
https://www.ncbi.nlm.nih.gov/pubmed/23825667
http://dx.doi.org/10.1371/journal.pone.0067532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692453/
https://www.ncbi.nlm.nih.gov/pubmed/23825667
http://dx.doi.org/10.1371/journal.pone.0067532

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