NGF Upregulates the Plasminogen Activation Inhibitor-1 in Neurons via the Calcineurin/NFAT Pathway and the Down Syndrome-Related Proteins DYRK1A and RCAN1 Attenuate This Effect

BACKGROUND: Plasminogen activator inhibitor 1 (PAI-1) is a key regulator of the plasminogen activation system. Although several lines of evidence support a significant role of PAI-1 in the brain, the regulation of its expression in neurons is poorly understood. In the present study we tested the hyp...

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Detalles Bibliográficos
Autores principales: Stefos, Georgios C., Soppa, Ulf, Dierssen, Mara, Becker, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692457/
https://www.ncbi.nlm.nih.gov/pubmed/23825664
http://dx.doi.org/10.1371/journal.pone.0067470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692457/
https://www.ncbi.nlm.nih.gov/pubmed/23825664
http://dx.doi.org/10.1371/journal.pone.0067470

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