Hydrazinocurcumin Encapsuled Nanoparticles “Re-Educate” Tumor-Associated Macrophages and Exhibit Anti-Tumor Effects on Breast Cancer Following STAT3 Suppression

Tumor-associated macrophages (TAMs) are essential cellular components within tumor microenvironment (TME). TAMs are educated by TME to transform to M2 polarized population, showing a M2-like phenotype, IL-10(high), IL-12(low), TGF-β(high). STAT3 signaling triggers crosstalk between tumor cells and T...

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Detalles Bibliográficos
Autores principales: Zhang, Xiwen, Tian, Wenxia, Cai, Xiaozhong, Wang, Xiaofei, Dang, Weiqi, Tang, Hao, Cao, Hong, Wang, Lin, Chen, Tingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692525/
https://www.ncbi.nlm.nih.gov/pubmed/23825527
http://dx.doi.org/10.1371/journal.pone.0065896

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