Attenuated RORC Expression in the Presence of EMT Progression in Somatotroph Adenomas following Treatment with Somatostatin Analogs Is Associated with Poor Clinical Recovery

Somatostatin analogs (SA) have been established as the first line medical treatment for acromegaly, but following long-term treatment, SA normalizes GH and IGF-I levels in only 40–60% of patients. The epithelial marker E-cadherin plays a crucial role in the epithelial mesenchymal transition (EMT) an...

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Detalles Bibliográficos
Autores principales: Lekva, Tove, Berg, Jens Petter, Heck, Ansgar, Lyngvi Fougner, Stine, Olstad, Ole Kristoffer, Ringstad, Geir, Bollerslev, Jens, Ueland, Thor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692554/
https://www.ncbi.nlm.nih.gov/pubmed/23825587
http://dx.doi.org/10.1371/journal.pone.0066927

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