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Genomic analysis of ERVWE2 locus in patients with multiple sclerosis: absence of genetic association but potential role of human endogenous retrovirus type W elements in molecular mimicry with myelin antigen
Human endogenous retroviruses (HERVs) arise from ancient infections of the host germline cells by exogenous retroviruses, constituting 8% of the human genome. Elevated level of envelope transcripts from HERVs-W has been detected in CSF, plasma and brain tissues from patients with Multiple Sclerosis...
Autores principales: | do Olival, Guilherme S., Faria, Thiago S., Nali, Luiz H. S., de Oliveira, Augusto C. P., Casseb, Jorge, Vidal, Jose E., Cavenaghi, Vitor B., Tilbery, Charles P., Moraes, Lenira, Fink, Maria C. S., Sumita, Laura M., Perron, Hervé, Romano, Camila M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693062/ https://www.ncbi.nlm.nih.gov/pubmed/23805135 http://dx.doi.org/10.3389/fmicb.2013.00172 |
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