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Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery

Type III protein secretion systems are being considered for vaccine development since virtually any protein antigen can be engineered for delivery by these nanomachines into the class I antigen presentation pathway to stimulate antigen-specific CD8(+) T cells (12). A limitation in the use of this sy...

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Detalles Bibliográficos
Autores principales:	Carleton, Heather A., Lara-Tejero, María, Liu, Xiaoyun, Galán, Jorge E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693737/ https://www.ncbi.nlm.nih.gov/pubmed/23481398 http://dx.doi.org/10.1038/ncomms2594

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