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Activation of the mitochondrial ATP-sensitive K(+) channel reduces apoptosis of spleen mononuclear cells induced by hyperlipidemia

BACKGROUND: We have previously demonstrated that increased rates of superoxide generation by extra-mitochondrial enzymes induce the activation of the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) in the livers of hypertriglyceridemic (HTG) mice. The resulting mild uncoupling mediated by...

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Detalles Bibliográficos
Autores principales:	Alberici, Luciane C, Paim, Bruno A, Zecchin, Karina G, Mirandola, Sandra R, Pestana, Cezar R, Castilho, Roger F, Vercesi, Anibal E, Oliveira, Helena CF
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693968/ https://www.ncbi.nlm.nih.gov/pubmed/23764148 http://dx.doi.org/10.1186/1476-511X-12-87

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