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Evolution of genetic switch complexity
The circuitry of the phage λ genetic switch determining the outcome of lytic or lysogenic growth is well-integrated and complex, raising the question as to how it evolved. It is plausible that it arose from a simpler ancestral switch with fewer components that underwent various additions and refinem...
Autores principales: | Broussard, Gregory W., Hatfull, Graham F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694055/ https://www.ncbi.nlm.nih.gov/pubmed/23819104 http://dx.doi.org/10.4161/bact.24186 |
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