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An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo
Afadin is an intracellular binding partner of nectins, cell-cell adhesion molecules, and plays important roles in the formation of cell-cell junctions. Afadin-knockout mice show early embryonic lethality, therefore little is known about the function of afadin during organ development. In this study,...
Autores principales: | Majima, Takashi, Takeuchi, Keisuke, Sano, Keigo, Hirashima, Masanori, Zankov, Dimitar P., Tanaka-Okamoto, Miki, Ishizaki, Hiroyoshi, Miyoshi, Jun, Ogita, Hisakazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694064/ https://www.ncbi.nlm.nih.gov/pubmed/23840823 http://dx.doi.org/10.1371/journal.pone.0068134 |
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