The Immunosuppressant Protosappanin A Promotes Dendritic Cell-Mediated Expansion of Alloantigen-Specific Tregs and Prolongs Allograft Survival in Rats

Protosappanin A (PrA), an immunosuppressive ingredient of the medicinal herb Caesalpinia sappan L, prolongs heart allograft survival in rats, possibly by impairing the function of antigen-presenting cells (APCs). We examined the effects of PrA on the maturation and function of dendritic cells (DCs),...

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Detalles Bibliográficos
Autores principales: Zhang, Maomao, Zhang, Shuo, Wu, Jian, Sun, Yong, Li, Lili, Du, Wenjuan, Liu, Jingjin, Hou, Jingbo, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694094/
https://www.ncbi.nlm.nih.gov/pubmed/23840445
http://dx.doi.org/10.1371/journal.pone.0066336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694094/
https://www.ncbi.nlm.nih.gov/pubmed/23840445
http://dx.doi.org/10.1371/journal.pone.0066336

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