Cargando…

The Immunosuppressant Protosappanin A Promotes Dendritic Cell-Mediated Expansion of Alloantigen-Specific Tregs and Prolongs Allograft Survival in Rats

Protosappanin A (PrA), an immunosuppressive ingredient of the medicinal herb Caesalpinia sappan L, prolongs heart allograft survival in rats, possibly by impairing the function of antigen-presenting cells (APCs). We examined the effects of PrA on the maturation and function of dendritic cells (DCs),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Maomao, Zhang, Shuo, Wu, Jian, Sun, Yong, Li, Lili, Du, Wenjuan, Liu, Jingjin, Hou, Jingbo, Yu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694094/ https://www.ncbi.nlm.nih.gov/pubmed/23840445 http://dx.doi.org/10.1371/journal.pone.0066336

Ejemplares similares

The Immunosuppressant Protosappanin A Diminished Recipient T Cell Migration into Allograft via Inhibition of IP-10 in Rat Heart Transplant
por: Zhang, Maomao, et al.
Publicado: (2014)

Thalidomide with blockade of co-stimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts
por: Zhu, Maoshu, et al.
Publicado: (2020)

Correction: Thalidomide with blockade of costimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts
por: Zhu, Maoshu, et al.
Publicado: (2022)

Identification, selection, and expansion of non-gene modified alloantigen-reactive Tregs for clinical therapeutic use
por: Alzhrani, Alaa, et al.
Publicado: (2020)

iPSC-Derived Regulatory Dendritic Cells Inhibit Allograft Rejection by Generating Alloantigen-Specific Regulatory T Cells
por: Cai, Songjie, et al.
Publicado: (2017)

Protosappanin B promotes apoptosis and causes G(1) cell cycle arrest in human bladder cancer cells
por: Yang, Xihua, et al.
Publicado: (2019)

Lymphatic Reconstruction in Kidney Allograft Aggravates Chronic Rejection by Promoting Alloantigen Presentation
por: Lin, Jinwen, et al.
Publicado: (2021)

Inhibition of Dectin-1 on Dendritic Cells Prevents Maturation and Prolongs Murine Islet Allograft Survival
por: Ren, Ao, et al.
Publicado: (2021)

Corrigendum: Lymphatic reconstruction in kidney allograft aggravates chronic rejection by promoting alloantigen presentation
por: Lin, Jinwen, et al.
Publicado: (2022)

Antigen-specific expansion and differentiation of natural killer cells by alloantigen stimulation
por: Nabekura, Tsukasa, et al.
Publicado: (2014)

Protosappanin‐A and oleanolic acid protect injured podocytes from apoptosis through inhibition of AKT‐mTOR signaling
por: Zheng, Jiaxin, et al.
Publicado: (2019)

Alloantigen Infusion Activates the Transcriptome of Type 2 Conventional Dendritic Cells
por: Schroth, Samantha L., et al.
Publicado: (2023)

Linking erythropoietin to Treg-dependent allograft survival through myeloid cells
por: Horwitz, Julian K., et al.
Publicado: (2022)

Protosappanin B Exerts Anti-tumor Effects on Colon Cancer Cells via Inhibiting GOLPH3 Expression
por: Zheng, Xue-Cong, et al.
Publicado: (2020)

Simultaneous determination of brazilin and protosappanin B in Caesalpinia sappan by ionic-liquid dispersive liquid-phase microextraction method combined with HPLC
por: Xia, Zhaoyang, et al.
Publicado: (2017)

Dendritic Cells Promote Treg Expansion but Not Th17 Generation in Response to Talaromyces marneffei Yeast Cells
por: Tang, Yanping, et al.
Publicado: (2020)

Protosappanin A protects against atherosclerosis via anti- hyperlipidemia, anti-inflammation and NF-κB signaling pathway in hyperlipidemic rabbits
por: Huang, Ying, et al.
Publicado: (2018)

Withaferin A inhibits lymphocyte proliferation, dendritic cell maturation in vitro and prolongs islet allograft survival
por: Kumano, Kenjiro, et al.
Publicado: (2021)

Inhibition of DAI refrains dendritic cells from maturation and prolongs murine islet and skin allograft survival
por: Cheng, Pengrui, et al.
Publicado: (2023)

SPONTANEOUS RELEASE OF T-CELL RECEPTORS FOR ALLOANTIGENS : I. RECOGNITION OF ALLOANTIGENS AND RECEPTOR RELEASE DYNAMICS
por: Ramseier, Hansruedy
Publicado: (1974)

Specific immunosuppression by mixed chimerism with bone marrow transplantation after Staphylococcal Enterotoxin B pretreatment could prolong corneal allograft survival in mice
por: Zhang, Yingnan, et al.
Publicado: (2012)

Dendritic Cells Transduced with Single Immunoglobulin IL-1-Related Receptor Exhibit Immature Properties and Prolong Islet Allograft Survival
por: Xue, Zhicheng, et al.
Publicado: (2017)

SURFACE ALLOANTIGENS OF PLASMA CELLS
por: Takahashi, Toshitada, et al.
Publicado: (1970)

B-lymphocyte alloantigens in Caucasians
Publicado: (1976)

hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts
por: Todorova, Dilyana, et al.
Publicado: (2020)

Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection
por: Ye, Qing, et al.
Publicado: (2017)

Migratory behavior of lymphocytes with specific reactivity to alloantigens. II. Selective recruitment to lymphoid cell allografts and their draining lymph nodes
Publicado: (1978)

Specific suppression of allograft rejection by trinitrophenyl (TNP)- induced suppressor cells in recipients treated with TNP-haptenated donor alloantigens
Publicado: (1985)

In Utero Exposure to Exosomal and B-Cell Alloantigens Lessens Alloreactivity of Recipients’ Lymphocytes Rather than Confers Allograft Tolerance
por: Chen, Jeng-Chang, et al.
Publicado: (2018)

Tumors recycle glucocorticoids to drive Treg-mediated immunosuppression
por: Swatler, Julian, et al.
Publicado: (2023)

CD8+CD122+PD-1+ Tregs Synergize With Costimulatory Blockade of CD40/CD154, but Not B7/CD28, to Prolong Murine Allograft Survival
por: Liu, Huazhen, et al.
Publicado: (2019)

Wnt1 Inhibits Hydrogen Peroxide-Induced Apoptosis in Mouse Cardiac Stem Cells
por: Liu, Jingjin, et al.
Publicado: (2013)

HLA-G Dimers in the Prolongation of Kidney Allograft Survival
por: Ezeakile, Maureen, et al.
Publicado: (2014)

Prolongation of allograft survival by passenger donor regulatory T cells
por: Harper, Ines G., et al.
Publicado: (2019)

Alloantigen receptors on activated T cells in mice. I. Binding of alloantigens and anti-idiotypic antibodies to the same receptors
Publicado: (1978)

Relative Frequencies of Alloantigen-Specific Helper CD4 T Cells and B Cells Determine Mode of Antibody-Mediated Allograft Rejection
por: Alsughayyir, Jawaher, et al.
Publicado: (2019)

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127(pos) Depletion, Treg Expansion, and Treg Cryopreservation
por: Peters, Jorieke H., et al.
Publicado: (2008)

The contribution of mutant amino acids to alloantigenicity
Publicado: (1989)

Dendritic Cells Decreased the Concomitant Expanded Tregs and Tregs Related IL-35 in Cytokine-Induced Killer Cells and Increased Their Cytotoxicity against Leukemia Cells
por: Pan, Ying, et al.
Publicado: (2014)

EXCELLENT ALLOGRAFT RECOVERY DESPITE PROLONGED SARS-COV-2 SHEDDING AFTER REDUCTION OF IMMUNOSUPPRESSION IN LUNG TRANSPLANT RECIPIENT
por: RAZIA, DEEPIKA, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sti7ugtn10te6aelaulu3rfpjc