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Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices

Airway remodelling, including smooth muscle remodelling, is a primary cause of airflow limitation in asthma. Recent evidence links bronchoconstriction to airway remodelling in asthma. The mechanisms involved are poorly understood. A possible player is the multifunctional cytokine TGF-β, which plays...

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Detalles Bibliográficos
Autores principales:	Oenema, Tjitske A., Maarsingh, Harm, Smit, Marieke, Groothuis, Geny M. M., Meurs, Herman, Gosens, Reinoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694103/ https://www.ncbi.nlm.nih.gov/pubmed/23840342 http://dx.doi.org/10.1371/journal.pone.0065580

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