Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish

Charcot-Marie-Tooth disease (CMT) represents a group of neurodegenerative disorders typically characterised by demyelination (CMT1) or distal axon degeneration (CMT2) of motor and sensory neurons. The majority of CMT2 cases are caused by mutations in mitofusin 2 (MFN2); an essential gene encoding a...

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Detalles Bibliográficos
Autores principales: Chapman, Anna L., Bennett, Ellen J., Ramesh, Tennore M., De Vos, Kurt J., Grierson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694133/
https://www.ncbi.nlm.nih.gov/pubmed/23840650
http://dx.doi.org/10.1371/journal.pone.0067276

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