Industrial Scale Isolation, Structural and Spectroscopic Characterization of Epiisopiloturine from Pilocarpus microphyllus Stapf Leaves: A Promising Alkaloid against Schistosomiasis

This paper presents an industrial scale process for extraction, purification, and isolation of epiisopiloturine (EPI) (2(3H)-Furanone,dihydro-3-(hydroxyphenylmethyl)-4-[(1-methyl-1H-imidazol-4-yl)methyl]-, [3S-[3a(R*),4b]]), which is an alkaloid from jaborandi leaves (Pilocarpus microphyllus Stapf)....

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Detalles Bibliográficos
Autores principales: Véras, Leiz M. C., Cunha, Vanessa R. R., Lima, Filipe C. D. A., Guimarães, Maria A., Vieira, Marianne M., Campelo, Yuri D. M., Sakai, Vanessa Y., Lima, David F., Carvalho Jr, Paulo S., Ellena, Javier A., Silva, Paulo R. P., Vasconcelos, Luciene C., Godejohann, Markus, Petrilli, Helena M., Constantino, Vera R. L., Mascarenhas, Yvonne P., de Souza de Almeida Leite, José Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694155/
https://www.ncbi.nlm.nih.gov/pubmed/23840522
http://dx.doi.org/10.1371/journal.pone.0066702

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