Cargando…
Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE(−/−) Mice Fed a High-Fat/High-Cholesterol Diet
AIMS: Atherosclerosis is a chronic inflammatory disease and represents the major cause of cardiovascular morbidity and mortality. There is evidence that dihydrocapsaicin (DHC) can exert multiple pharmacological and physiological effects. Here, we explored the effect of DHC in atherosclerotic plaque...
Autores principales: | Hu, Yan-Wei, Ma, Xin, Huang, Jin-Lan, Mao, Xin-Ru, Yang, Jun-Yao, Zhao, Jia-Yi, Li, Shu-Fen, Qiu, Yu-Rong, Yang, Jia, Zheng, Lei, Wang, Qian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694162/ https://www.ncbi.nlm.nih.gov/pubmed/23840542 http://dx.doi.org/10.1371/journal.pone.0066876 |
Ejemplares similares
-
Dihydrocapsaicin down-regulates apoM expression through inhibiting Foxa2 expression and enhancing LXRα expression in HepG2 cells
por: Zhao, Jia-Yi, et al.
Publicado: (2014) -
Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ(−/−), PPARδ(−/−), PPARγδ(−/−), or LXRαβ(−/−) bone marrow
por: Marathe, Chaitra, et al.
Publicado: (2009) -
Nur77 Decreases Atherosclerosis Progression in apoE(−/−) Mice Fed a High-Fat/High-Cholesterol Diet
por: Hu, Yan-Wei, et al.
Publicado: (2014) -
VNN1 promotes atherosclerosis progression in apoE(−/−) mice fed a high-fat/high-cholesterol diet
por: Hu, Yan-Wei, et al.
Publicado: (2016) -
Sonodynamic therapy-induced foam cells apoptosis activates the phagocytic PPARγ-LXRα-ABCA1/ABCG1 pathway and promotes cholesterol efflux in advanced plaque
por: Wang, Huan, et al.
Publicado: (2018)