Cargando…
A simple tool to improve pluripotent stem cell differentiation
We develop a method to overcome previously documented restrictions on the differentiation propensities of pluripotent stem cells. Culturing pluripotent stem cells in dimethylsulfoxide (DMSO) activates the retinoblastoma protein, increases the proportion of cells in the early G1 phase of the cell cyc...
Autores principales: | Chetty, Sundari, Pagliuca, Felicia Walton, Honore, Christian, Kweudjeu, Anastasie, Rezania, Alireza, Melton, Douglas A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694177/ https://www.ncbi.nlm.nih.gov/pubmed/23584186 http://dx.doi.org/10.1038/nmeth.2442 |
Ejemplares similares
-
A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation
por: Chetty, Sundari, et al.
Publicado: (2015) -
An improved ScoreCard to assess the differentiation potential of human pluripotent stem cells
por: Tsankov, Alexander M., et al.
Publicado: (2015) -
Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation
por: Shcherbina, Anna, et al.
Publicado: (2019) -
A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family
por: Li, Jingling, et al.
Publicado: (2018) -
Generation of stem cell-derived β-cells from patients with type 1 diabetes
por: Millman, Jeffrey R., et al.
Publicado: (2016)