A personalised approach to prostate cancer screening based on genotyping of risk founder alleles

BACKGROUND: To evaluate whether genotyping for 18 prostate cancer founder variants is helpful in identifying high-risk individuals and for determining optimal screening regimens. METHODS: A serum PSA level was measured and a digital rectal examination (DRE) was performed on 2907 unaffected men aged...

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Detalles Bibliográficos
Autores principales: Cybulski, C, Wokołorczyk, D, Kluźniak, W, Kashyap, A, Gołąb, A, Słojewski, M, Sikorski, A, Puszyński, M, Soczawa, M, Borkowski, T, Borkowski, A, Antczak, A, Przybyła, J, Sosnowski, M, Małkiewicz, B, Zdrojowy, R, Domagała, P, Piotrowski, K, Menkiszak, J, Krzystolik, K, Gronwald, J, Jakubowska, A, Górski, B, Dębniak, T, Masojć, B, Huzarski, T, Muir, K R, Lophatananon, A, Lubiński, J, Narod, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694242/
https://www.ncbi.nlm.nih.gov/pubmed/23722471
http://dx.doi.org/10.1038/bjc.2013.261

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