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Estimating single nucleotide polymorphism associations using pedigree data: applications to breast cancer

BACKGROUND: Pedigrees with multiple genotyped family members have been underutilised in breast cancer (BC) genetic-association studies. We developed a pedigree-based analytical framework to characterise single-nucleotide polymorphism (SNP) associations with BC risk using data from 736 BC families as...

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Detalles Bibliográficos
Autores principales:	Barnes, D R, Barrowdale, D, Beesley, J, Chen, X, James, P A, Hopper, J L, Goldgar, D, Chenevix-Trench, G, Antoniou, A C, Mitchell, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694253/ https://www.ncbi.nlm.nih.gov/pubmed/23756864 http://dx.doi.org/10.1038/bjc.2013.277

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