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Synthesis and in Vitro and in Vivo Characterization of Highly β(1)-Selective β-Adrenoceptor Partial Agonists

[Image: see text] β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β(1)-selective molecules exist. To...

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Detalles Bibliográficos
Autores principales:	Mistry, Shailesh N., Baker, Jillian G, Fischer, Peter M, Hill, Stephen J, Gardiner, Sheila M, Kellam, Barrie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694353/ https://www.ncbi.nlm.nih.gov/pubmed/23614528 http://dx.doi.org/10.1021/jm400348g

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