U1snRNP-mediated suppression of polyadenylation in conjunction with the RNA structure controls poly (A) site selection in foamy viruses

BACKGROUND: During reverse transcription, retroviruses duplicate the long terminal repeats (LTRs). These identical LTRs carry both promoter regions and functional polyadenylation sites. To express full-length transcripts, retroviruses have to suppress polyadenylation in the 5′LTR and activate polyad...

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Detalles Bibliográficos
Autores principales: Schrom, Eva-Maria, Moschall, Rebecca, Hartl, Maximilian J, Weitner, Helena, Fecher, David, Langemeier, Jörg, Bohne, Jens, Wöhrl, Birgitta M, Bodem, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694450/
https://www.ncbi.nlm.nih.gov/pubmed/23718736
http://dx.doi.org/10.1186/1742-4690-10-55

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