Time is of the essence for ParaHox homeobox gene clustering

ParaHox genes, and their evolutionary sisters the Hox genes, are integral to patterning the anterior-posterior axis of most animals. Like the Hox genes, ParaHox genes can be clustered and exhibit the phenomenon of colinearity - gene order within the cluster matching gene activation. Two new instance...

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Detalles Bibliográficos
Autores principales: Garstang, Myles, Ferrier, David EK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694477/
https://www.ncbi.nlm.nih.gov/pubmed/23803337
http://dx.doi.org/10.1186/1741-7007-11-72
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author Garstang, Myles
Ferrier, David EK
author_facet Garstang, Myles
Ferrier, David EK
author_sort Garstang, Myles
collection PubMed
description ParaHox genes, and their evolutionary sisters the Hox genes, are integral to patterning the anterior-posterior axis of most animals. Like the Hox genes, ParaHox genes can be clustered and exhibit the phenomenon of colinearity - gene order within the cluster matching gene activation. Two new instances of ParaHox clustering provide the first examples of intact clusters outside chordates, with gene expression lending weight to the argument that temporal colinearity is the key to understanding clustering. See research articles: http://www.biomedcentral.com/1741-7007/11/68 and http://www.biomedcentral.com/1471-2148/13/129
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spelling pubmed-36944772013-06-28 Time is of the essence for ParaHox homeobox gene clustering Garstang, Myles Ferrier, David EK BMC Biol Commentary ParaHox genes, and their evolutionary sisters the Hox genes, are integral to patterning the anterior-posterior axis of most animals. Like the Hox genes, ParaHox genes can be clustered and exhibit the phenomenon of colinearity - gene order within the cluster matching gene activation. Two new instances of ParaHox clustering provide the first examples of intact clusters outside chordates, with gene expression lending weight to the argument that temporal colinearity is the key to understanding clustering. See research articles: http://www.biomedcentral.com/1741-7007/11/68 and http://www.biomedcentral.com/1471-2148/13/129 BioMed Central 2013-06-26 /pmc/articles/PMC3694477/ /pubmed/23803337 http://dx.doi.org/10.1186/1741-7007-11-72 Text en Copyright © 2013 Garstang and Ferrier; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Garstang, Myles
Ferrier, David EK
Time is of the essence for ParaHox homeobox gene clustering
title Time is of the essence for ParaHox homeobox gene clustering
title_full Time is of the essence for ParaHox homeobox gene clustering
title_fullStr Time is of the essence for ParaHox homeobox gene clustering
title_full_unstemmed Time is of the essence for ParaHox homeobox gene clustering
title_short Time is of the essence for ParaHox homeobox gene clustering
title_sort time is of the essence for parahox homeobox gene clustering
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694477/
https://www.ncbi.nlm.nih.gov/pubmed/23803337
http://dx.doi.org/10.1186/1741-7007-11-72
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