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Hard-wired heterogeneity in blood stem cells revealed using a dynamic regulatory network model
Motivation: Combinatorial interactions of transcription factors with cis-regulatory elements control the dynamic progression through successive cellular states and thus underpin all metazoan development. The construction of network models of cis-regulatory elements, therefore, has the potential to g...
Autores principales: | Bonzanni, Nicola, Garg, Abhishek, Feenstra, K. Anton, Schütte, Judith, Kinston, Sarah, Miranda-Saavedra, Diego, Heringa, Jaap, Xenarios, Ioannis, Göttgens, Berthold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694641/ https://www.ncbi.nlm.nih.gov/pubmed/23813012 http://dx.doi.org/10.1093/bioinformatics/btt243 |
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