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GeneScissors: a comprehensive approach to detecting and correcting spurious transcriptome inference owing to RNA-seq reads misalignment

Motivation: RNA-seq techniques provide an unparalleled means for exploring a transcriptome with deep coverage and base pair level resolution. Various analysis tools have been developed to align and assemble RNA-seq data, such as the widely used TopHat/Cufflinks pipeline. A common observation is that...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaojun, Huang, Shunping, Wang, Jack, Zhang, Xiang, Pardo Manuel de Villena, Fernando, McMillan, Leonard, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694649/
https://www.ncbi.nlm.nih.gov/pubmed/23812996
http://dx.doi.org/10.1093/bioinformatics/btt216

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