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GeneScissors: a comprehensive approach to detecting and correcting spurious transcriptome inference owing to RNA-seq reads misalignment
Motivation: RNA-seq techniques provide an unparalleled means for exploring a transcriptome with deep coverage and base pair level resolution. Various analysis tools have been developed to align and assemble RNA-seq data, such as the widely used TopHat/Cufflinks pipeline. A common observation is that...
Autores principales: | Zhang, Zhaojun, Huang, Shunping, Wang, Jack, Zhang, Xiang, Pardo Manuel de Villena, Fernando, McMillan, Leonard, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694649/ https://www.ncbi.nlm.nih.gov/pubmed/23812996 http://dx.doi.org/10.1093/bioinformatics/btt216 |
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