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ThreaDom: extracting protein domain boundary information from multiple threading alignments

Motivation: Protein domains are subunits that can fold and evolve independently. Identification of domain boundary locations is often the first step in protein folding and function annotations. Most of the current methods deduce domain boundaries by sequence-based analysis, which has low accuracy. T...

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Detalles Bibliográficos
Autores principales: Xue, Zhidong, Xu, Dong, Wang, Yan, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694664/
https://www.ncbi.nlm.nih.gov/pubmed/23812990
http://dx.doi.org/10.1093/bioinformatics/btt209