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Using state machines to model the Ion Torrent sequencing process and to improve read error rates

Motivation: The importance of fast and affordable DNA sequencing methods for current day life sciences, medicine and biotechnology is hard to overstate. A major player is Ion Torrent, a pyrosequencing-like technology which produces flowgrams – sequences of incorporation values – which are converted...

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Detalles Bibliográficos
Autores principales: Golan, David, Medvedev, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694666/
https://www.ncbi.nlm.nih.gov/pubmed/23813003
http://dx.doi.org/10.1093/bioinformatics/btt212