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Using state machines to model the Ion Torrent sequencing process and to improve read error rates
Motivation: The importance of fast and affordable DNA sequencing methods for current day life sciences, medicine and biotechnology is hard to overstate. A major player is Ion Torrent, a pyrosequencing-like technology which produces flowgrams – sequences of incorporation values – which are converted...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694666/ https://www.ncbi.nlm.nih.gov/pubmed/23813003 http://dx.doi.org/10.1093/bioinformatics/btt212 |