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Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/Robo Activity at the Heart Lumen

The Drosophila heart tube represents a structure that similarly to vertebrates' primary heart tube exhibits a large lumen; the mechanisms promoting heart tube morphology in both Drosophila and vertebrates are poorly understood. We identified Multiplexin (Mp), the Drosophila orthologue of mammal...

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Detalles Bibliográficos
Autores principales:	Harpaz, Nofar, Ordan, Elly, Ocorr, Karen, Bodmer, Rolf, Volk, Talila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694841/ https://www.ncbi.nlm.nih.gov/pubmed/23825967 http://dx.doi.org/10.1371/journal.pgen.1003597

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