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Evasion of Antiviral Innate Immunity by Theiler's Virus L* Protein through Direct Inhibition of RNase L

Theiler's virus is a neurotropic picornavirus responsible for chronic infections of the central nervous system. The establishment of a persistent infection and the subsequent demyelinating disease triggered by the virus depend on the expression of L*, a viral accessory protein encoded by an alt...

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Detalles Bibliográficos
Autores principales: Sorgeloos, Frédéric, Jha, Babal Kant, Silverman, Robert H., Michiels, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694852/
https://www.ncbi.nlm.nih.gov/pubmed/23825954
http://dx.doi.org/10.1371/journal.ppat.1003474