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Hepatitis B Virus Induces IL-23 Production in Antigen Presenting Cells and Causes Liver Damage via the IL-23/IL-17 Axis
IL-23 regulates myriad processes in the innate and adaptive immune systems, and is a critical mediator of the proinflammatory effects exerted by Th17 cells in many diseases. In this study, we investigated whether and how hepatitis B virus (HBV) causes liver damage directly through the IL-23 signalin...
Autores principales: | Wang, Qinghong, Zhou, Jijun, Zhang, Bei, Tian, Zhiqiang, Tang, Jun, Zheng, Yanhua, Huang, Zemin, Tian, Yi, Jia, Zhengcai, Tang, Yan, van Velkinburgh, Jennifer C., Mao, Qing, Bian, Xiuwu, Ping, Yifang, Ni, Bing, Wu, Yuzhang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694858/ https://www.ncbi.nlm.nih.gov/pubmed/23825942 http://dx.doi.org/10.1371/journal.ppat.1003410 |
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