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Host Factor SAMHD1 Restricts DNA Viruses in Non-Dividing Myeloid Cells

SAMHD1 is a newly identified anti-HIV host factor that has a dNTP triphosphohydrolase activity and depletes intracellular dNTP pools in non-dividing myeloid cells. Since DNA viruses utilize cellular dNTPs, we investigated whether SAMHD1 limits the replication of DNA viruses in non-dividing myeloid t...

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Detalles Bibliográficos
Autores principales:	Hollenbaugh, Joseph A., Gee, Peter, Baker, Jonathon, Daly, Michele B., Amie, Sarah M., Tate, Jessica, Kasai, Natsumi, Kanemura, Yuka, Kim, Dong-Hyun, Ward, Brian M., Koyanagi, Yoshio, Kim, Baek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694861/ https://www.ncbi.nlm.nih.gov/pubmed/23825958 http://dx.doi.org/10.1371/journal.ppat.1003481

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