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Prioritizing Potentially Druggable Mutations with dGene: An Annotation Tool for Cancer Genome Sequencing Data
A major goal of cancer genome sequencing is to identify mutations or other somatic alterations that can be targeted by selective and specific drugs. dGene is an annotation tool designed to rapidly identify genes belonging to one of ten druggable classes that are frequently targeted in cancer drug de...
Autores principales: | Kumar, Runjun D., Chang, Li-Wei, Ellis, Matthew J., Bose, Ron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694871/ https://www.ncbi.nlm.nih.gov/pubmed/23826350 http://dx.doi.org/10.1371/journal.pone.0067980 |
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