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Clinical Relevance of Minimal Residual Viremia during Long-Term Therapy with Nucleos(t)ide Analogues in Patients with Chronic Hepatitis B

BACKGROUND: Successful therapy of chronic hepatitis B with nucleos(t)ide analogues (NUCs) has been defined by undetectable HBV-DNA determined with conventional PCR (lower limit of detection (LLD) 60–80 IU/mL) in clinical registration trials. However, current EASL guidelines recommend highly sensitiv...

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Detalles Bibliográficos
Autores principales:	Maier, Melanie, Liebert, Uwe G., Wittekind, Christian, Kaiser, Thorsten, Berg, Thomas, Wiegand, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694892/ https://www.ncbi.nlm.nih.gov/pubmed/23826307 http://dx.doi.org/10.1371/journal.pone.0067481

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