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Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB

BACKGROUND: Early secretory antigenic target 6 (ESAT-6) and culture filtrate protein 10 (CFP-10) are Mycobacterium tuberculosis (Mtb)–specific antigens that are secreted by actively metabolising bacteria and contribute to the virulence of the bacteria. Their ability to induce Treg and Th2 responses,...

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Detalles Bibliográficos
Autores principales:	Jackson-Sillah, Dolly, Cliff, Jacqueline M., Mensah, Gloria Ivy, Dickson, Emmanuel, Sowah, Sandra, Tetteh, John K A., Addo, Kwasi K., Ottenhoff, Tom H. M., Bothamley, Graham, Dockrell, Hazel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694917/ https://www.ncbi.nlm.nih.gov/pubmed/23826366 http://dx.doi.org/10.1371/journal.pone.0068121

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