Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates

An UPLC-MS/MS method was developed for the determination of serotonin (5-HT), dopamine (DA), their phase I metabolites 5-HIAA, DOPAC and HVA, and their sulfate and glucuronide conjugates in human brain microdialysis samples obtained from two patients with acute brain injuries, ventricular cerebrospi...

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Detalles Bibliográficos
Autores principales: Suominen, Tina, Uutela, Päivi, Ketola, Raimo A., Bergquist, Jonas, Hillered, Lars, Finel, Moshe, Zhang, Hongbo, Laakso, Aki, Kostiainen, Risto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694921/
https://www.ncbi.nlm.nih.gov/pubmed/23826355
http://dx.doi.org/10.1371/journal.pone.0068007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694921/
https://www.ncbi.nlm.nih.gov/pubmed/23826355
http://dx.doi.org/10.1371/journal.pone.0068007

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