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Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation
The lipid lamellae in the stratum corneum is important for the epidermal permeability barrier. The lipid lamellae component ceramide (CER), comprising an ultra long-chain (ULC) fatty acid (FA) of ≥26 carbons (ULC CER), plays an essential role in barrier formation. ULC acyl-CoAs, produced by the FA e...
Autores principales: | Mizutani, Yukiko, Sun, Hui, Ohno, Yusuke, Sassa, Takayuki, Wakashima, Takeshi, Obara, Mari, Yuyama, Kohei, Kihara, Akio, Igarashi, Yasuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694974/ https://www.ncbi.nlm.nih.gov/pubmed/23826266 http://dx.doi.org/10.1371/journal.pone.0067317 |
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