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Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons

The peripheral terminals of primary sensory neurons detect histamine and non-histamine itch-provoking ligands through molecularly distinct transduction mechanisms. It remains unclear, however, whether these distinct pruritogens activate the same or different afferent fibers. We utilized a strategy o...

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Detalles Bibliográficos
Autores principales: Roberson, David P., Gudes, Sagi, Sprague, Jared M., Patoski, Haley A. W., Robson, Victoria K., Blasl, Felix, Duan, Bo, Oh, Seog Bae, Bean, Bruce P., Ma, Qiufu, Binshtok, Alexander M., Woolf, Clifford J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695070/
https://www.ncbi.nlm.nih.gov/pubmed/23685721
http://dx.doi.org/10.1038/nn.3404