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Blood Clotting Factor VIII: From Evolution to Therapy
Recombinant blood clotting factor VIII is one of the most complex proteins for industrial manufacturing due to the low efficiency of its gene transcription, massive intracellular loss of its proprotein during post-translational processing, and the instability of the secreted protein. Improvement in...
Autores principales: | Orlova, N. A., Kovnir, S. V., Vorobiev, I. I., Gabibov, A. G., Vorobiev, A. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695351/ https://www.ncbi.nlm.nih.gov/pubmed/23819034 |
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