The Evolutionary Pathway of X Chromosome Inactivation in Mammals

X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inac...

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Autores principales: Shevchenko, A.I., Zakharova, I.S., Zakian, S.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695352/
https://www.ncbi.nlm.nih.gov/pubmed/23819035
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author Shevchenko, A.I.
Zakharova, I.S.
Zakian, S.M.
author_facet Shevchenko, A.I.
Zakharova, I.S.
Zakian, S.M.
author_sort Shevchenko, A.I.
collection PubMed
description X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inactivation processes in marsupial and eutherian mammals are considered, and the hypotheses on its origin and evolution are discussed in this review.
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spelling pubmed-36953522013-07-01 The Evolutionary Pathway of X Chromosome Inactivation in Mammals Shevchenko, A.I. Zakharova, I.S. Zakian, S.M. Acta Naturae Review Article X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inactivation processes in marsupial and eutherian mammals are considered, and the hypotheses on its origin and evolution are discussed in this review. A.I. Gordeyev 2013 /pmc/articles/PMC3695352/ /pubmed/23819035 Text en Copyright © 2013 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shevchenko, A.I.
Zakharova, I.S.
Zakian, S.M.
The Evolutionary Pathway of X Chromosome Inactivation in Mammals
title The Evolutionary Pathway of X Chromosome Inactivation in Mammals
title_full The Evolutionary Pathway of X Chromosome Inactivation in Mammals
title_fullStr The Evolutionary Pathway of X Chromosome Inactivation in Mammals
title_full_unstemmed The Evolutionary Pathway of X Chromosome Inactivation in Mammals
title_short The Evolutionary Pathway of X Chromosome Inactivation in Mammals
title_sort evolutionary pathway of x chromosome inactivation in mammals
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695352/
https://www.ncbi.nlm.nih.gov/pubmed/23819035
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