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Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation
Steroid receptors were classically described for regulating transcription by binding to target gene promoters. However, genome-wide studies reveal that steroid receptors-binding sites are mainly located at intragenic regions. To determine the role of these sites, we examined the effect of progestins...
Autores principales: | Bertucci, Paola Y., Nacht, A. Silvina, Alló, Mariano, Rocha-Viegas, Luciana, Ballaré, Cecilia, Soronellas, Daniel, Castellano, Giancarlo, Zaurin, Roser, Kornblihtt, Alberto R., Beato, Miguel, Vicent, Guillermo P., Pecci, Adali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695497/ https://www.ncbi.nlm.nih.gov/pubmed/23640331 http://dx.doi.org/10.1093/nar/gkt327 |
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