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The 26S proteasome drives trinucleotide repeat expansions

Trinucleotide repeat (TNR) expansion is the causative mutation for at least 17 inherited neurological diseases. An important question in the field is which proteins drive the expansion process. This study reports that the multi-functional protein Sem1 is a novel driver of TNR expansions in budding y...

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Detalles Bibliográficos
Autores principales:	Concannon, Claire, Lahue, Robert S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695522/ https://www.ncbi.nlm.nih.gov/pubmed/23620289 http://dx.doi.org/10.1093/nar/gkt295

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