Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system

The universally conserved Kae1/Qri7/YgjD and Sua5/YrdC protein families have been implicated in growth, telomere homeostasis, transcription and the N6-threonylcarbamoylation (t(6)A) of tRNA, an essential modification required for translational fidelity by the ribosome. In bacteria, YgjD orthologues...

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Detalles Bibliográficos
Autores principales: Wan, Leo C. K., Mao, Daniel Y. L., Neculai, Dante, Strecker, Jonathan, Chiovitti, David, Kurinov, Igor, Poda, Gennadiy, Thevakumaran, Neroshan, Yuan, Fang, Szilard, Rachel K., Lissina, Elena, Nislow, Corey, Caudy, Amy A., Durocher, Daniel, Sicheri, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695523/
https://www.ncbi.nlm.nih.gov/pubmed/23620299
http://dx.doi.org/10.1093/nar/gkt322

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