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Monitoring eukaryotic and bacterial UDG repair activity with DNA-multifluorophore sensors

We report the development of simple fluorogenic probes that report on the activity of both bacterial and mammalian uracil–DNA glycosylase (UDG) enzymes. The probes are built from short, modified single-stranded oligonucleotides containing natural and unnatural bases. The combination of multiple fluo...

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Detalles Bibliográficos
Autores principales:	Ono, Toshikazu, Edwards, Sarah K., Wang, Shenliang, Jiang, Wei, Kool, Eric T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695528/ https://www.ncbi.nlm.nih.gov/pubmed/23644286 http://dx.doi.org/10.1093/nar/gkt309

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