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Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling

Endocannabinoids are small signaling lipids, with 2-arachidonoylglycerol (2-AG) implicated in modulating axonal growth and synaptic plasticity. The concept of short-range extracellular signaling by endocannabinoids is supported by the lack of trans-synaptic 2-AG signaling in mice lacking sn-1-diacyl...

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Detalles Bibliográficos
Autores principales: Keimpema, Erik, Alpár, Alán, Howell, Fiona, Malenczyk, Katarzyna, Hobbs, Carl, Hurd, Yasmin L., Watanabe, Masahiko, Sakimura, Kenji, Kano, Masanobu, Doherty, Patrick, Harkany, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695556/
https://www.ncbi.nlm.nih.gov/pubmed/23806960
http://dx.doi.org/10.1038/srep02093